Presenters and Affiliations:
- Mary Helen Witt, MD – Clinical Faculty, UVA Community Oncology
- Emily C. Ayers, MD, MSCE – Assistant Professor of Medicine, Division of Hematology/Oncology
- Craig A. Portell, MD – Associate Professor of Medicine, Division of Hematology/Oncology
Outline of Topics Presented:
- Introduction and Overview: The impact of CLL and therapeutic challenges.
- Case Studies and Treatment Strategies: Discussion of specific patient cases, their treatment history, and management strategies.
- COVID-19 and CLL Treatment: Addressing treatment choices in the era of COVID-19, including vaccine response and considerations.
- Mortality and Hospitalization Rates: Data on CLL patients’ outcomes during COVID-19.
- Minimal Residual Disease (MRD) Testing: Techniques and significance in treatment planning.
- BTK Inhibitors and Venetoclax: Discussion of their use, impact on MRD, and patient management.
- Clinical Decision Making: Approaches to treatment alterations based on MRD results and patient conditions.
- Future Directions in CLL Management: Insights into ongoing studies and evolving treatment strategies.
This educational video provides a comprehensive overview of the current landscape in CLL treatment, highlighting the challenges and advances in therapy, especially in the context of the COVID-19 pandemic. The presenters, all experts in the field of hematology and oncology, offer valuable insights into patient management, evolving treatments, and the importance of MRD in guiding therapy decisions.